All posts tagged: Research

CAC2 Special Community Webinar–G-CSF, Cancer Stem Cells and Relapsed Neuroblastoma: A New Study Opens Up Questions and Opportunities

May 27, 2015
Webinars No comments yet
During our May All-Member and Community webinar,  Scott Kennedy & Donna Ludwinski of Solving Kids' Cancer moderated for our guest presenter, Dr. Jason Shohet addressed the findings of a new study, "G-CSF Promotes Neuroblastoma Tumorigenicity and Metastasis via STAT3-dependent Cancer Stem Cell Activation" published in the journal Cancer Research that identified a potential link between the use of the ​growth factor's effect on cancer stem-like cells and progression and recurrence of neuroblastoma.  As senior author of the study, Dr. Shohet discussed the relevance of these findings within the current context of neuroblastoma patient care as well as the future treatment implications. Topics covered include: What [...] Read more

CAC2 Webinar–Incorporating Genomics into Pediatric Cancer Trials

March 24, 2015
Webinars No comments yet
During our March All-Member and Community webinar, our guests discussed the findings and outcomes of the February NCI scientific workshop dedicated to childhood cancer genomics. On February 4 and 5, the National Cancer Institute hosted a scientific workshop focused on childhood cancer genomics. Scientist and researchers from around the world met to discuss the state of genomics research in pediatric cancer and what opportunities exist for research going forward. The Coalition Against Childhood Cancer and the Alliance for Childhood Cancer co-hosted this debriefing webinar featuring workshop attendees, Dr. Greg Aune (NCI-NCRA, pediatric oncologist-UTSA, and pediatric cancer survivor), Susan Weiner (Children’s Cause for [...] Read more

CAC2 Webinar–An Introduction to NCI’s Childhood Cancer Genomics Scientific Workshop–SLIDE DECKS

January 29, 2015
Webinars No comments yet
On Thursday, January 29, CAC2 and the Alliance for Childhood Cancer co-hosted CAC2 member Donna Ludwinski of Solving Kids’ Cancer and Amy Bulman and Kelley Landy from the National Cancer Institute to discuss the upcoming NCI scientific workshop dedicated to childhood cancer genomics. The panelists graciously allowed us to share their slide deck. Donna Ludwinski has also made available the following document which is a recently published overview of this topic by Julia Glade Bender, Anupam Verma, and Joshua D. Schiffman: Translating Genomic Discoveries to the Clinic in Pediatric Oncology Read more

NCI Meeting Scheduled for Fri. Feb 21

February 14, 2014
Community News No comments yet

There will be a meeting next week at the National Cancer Institute (NCI) dedicated to pediatric cancer drug development. The National Cancer Institute (NCI) will hold its 64th Meeting of the Director’s Consumer Liaison Group (DCLG) on Friday, February 21, 2014 from 9:30 a.m. to 4:00 p.m. on the National Institutes of Health (NIH) Campus in Bethesda, MD. The meeting will focus on barriers to drug development in pediatric cancer research and will include participants from the pediatric cancer advocacy community, as well as private and public sector presenters. The panels will discuss the State of Pediatric Cancer Research, Potential […]

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Complete Remission Induced By Dendritic Cell Vaccine For Relapsed Neuroblastoma Patient

August 26, 2013
Collaborative Achievements No comments yet
This collaborative research effort was due to childhood cancer groups coming together as part of CAC2. One year after his last treatment, a six-year-old boy with recurrent neuroblastoma is in complete remission for his high-risk metastatic cancer. Doctors reported this case study in the January 2013 issue of Pediatrics, the journal of the American Academy of Pediatrics, which was funded in part by a joint grant from the Andrew McDonough B+ Foundation, Pierce Phillips Charity and Solving Kids' Cancer. Current treatments for high-risk neuroblastoma patients include chemotherapy, radiation therapy, surgery, stem cell transplant, and immunotherapy. Less than half of the [...] Read more
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